Al(OH)3 facilitated synthesis of water-soluble, magnetic, radiolabelled and fluorescent hydroxyapatite nanoparticles.

نویسندگان

  • X Cui
  • M A Green
  • P J Blower
  • D Zhou
  • Y Yan
  • W Zhang
  • K Djanashvili
  • D Mathe
  • D S Veres
  • K Szigeti
چکیده

Magnetic and fluorescent hydroxyapatite nanoparticles were synthesised using Al(OH)3-stabilised MnFe2O4 or Fe3O4 nanoparticles as precursors. They were readily and efficiently radiolabelled with (18)F. Bisphosphonate polyethylene glycol polymers were utilised to endow the nanoparticles with excellent colloidal stability in water and to incorporate cyclam for high affinity labelling with (64)Cu.

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منابع مشابه

Loughborough University Institutional Repository

Al(OH)(3) facilitated synthesis of water-soluble, magnetic, radiolabelled and uorescent hydroxyapatite nanoparticles This item was submitted to Loughborough University's Institutional Repository by the/an author.restricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Please cite the published version.

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Al(OH)3 facilitated synthesis of water-soluble, magnetic, radiolabelled and fluorescent hydroxyapatite nanoparticles† †Electronic supplementary information (ESI) available: Conjugation of NPs with dyes, radiolabelling for NPs, NMR spectra, XRD, IR, zeta potential, DLS size distribution, TEM images and TGA data of NPs, fluorescent images of NPs. See DOI: 10.1039/c5cc02259b Click here for additional data file.

[a] Division of Imaging Science, 4th Floor of Lambeth wing, St Thomas Hospital campus, King’s College London, SE1 7EH, London, UK [b] Department of physics, Strand campus, King’s College London, WC2R 2LS, London, UK [c] Department of Mathematical Science, Loughborough University, Loughborough, LE11 3TU, UK [d] School of Chemistry, University of Nottingham, Nottingham, NG7 2RD, UK [e] Department...

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عنوان ژورنال:
  • Chemical communications

دوره 51 45  شماره 

صفحات  -

تاریخ انتشار 2015